ELMO1 antibody (C-Term)

Catalog No. ABIN2788147

Product Details anti-ELMO1 Antibody

Target: ELMO1 (Engulfment and Cell Motility 1 (ELMO1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELMO1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TQTPPGMLAL DNMLYFAKHH QDAYIRIVLE NSSREDKHEC PFGRSSIELT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against ELMO1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ELMO1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 727 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ELMO1

Target: ELMO1 (Engulfment and Cell Motility 1 (ELMO1))

Alternative Name: ELMO1 (ELMO1 Products)

Synonyms: MGC68475 antibody, ELMO1 antibody, CED-12 antibody, CED12 antibody, ELMO-1 antibody, 6330578D22Rik antibody, C230095H21Rik antibody, ELMO1s antibody, im:7151147 antibody, wu:fq24e08 antibody, zgc:85612 antibody, engulfment and cell motility 1 antibody, engulfment and cell motility 1 S homeolog antibody, engulfment and cell motility 1 (ced-12 homolog, C. elegans) antibody, ELMO1 antibody, elmo1.S antibody, elmo1 antibody, Elmo1 antibody

Background: The protein encoded by this gene interacts with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes. Similarity to a C. elegans protein suggests that this protein may function in apoptosis and in cell migration. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
Alias Symbols: CED-12, CED12, ELMO-1, KIAA0281, MGC126406
Protein Interaction Partner: ZNF398, TRIM54, UBC, PTGS2, DOCK1, BAG3, FGD1, RHOG, HCK, JMJD6, DOCK2,
Protein Size: 727

Molecular Weight: 84 kDa

Gene ID: 9844

NCBI Accession: NM_014800, NP_055615

UniProt: Q92556