ALDH3A1 antibody (C-Term)

Catalog No. ABIN2788191

The Rabbit Polyclonal anti-ALDH3A1 antibody (ABIN2788191) specifically detects ALDH3A1 in WB and IHC. The antibody is reactive with Human, Rat, Mouse, Dog, Cow, Guinea Pig and Horse samples.

Quick Overview for ALDH3A1 antibody (C-Term) (ABIN2788191)

Target: ALDH3A1 (Aldehyde Dehydrogenase 3 Family, Member A1 (ALDH3A1))

Reactivity: Human, Rat, Mouse, Dog, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH3A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ALDH3A1 Antibody

Binding Specificity: C-Term

Purpose: ALDH3A1 Antibody - C-terminal region

Sequence: KFMNSGQTCV APDYILCDPS IQNQIVEKLK KSLKEFYGED AKKSRDYGRI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ALDH3A1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ALDH3A1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59747-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ALDH3A1

Target: ALDH3A1 (Aldehyde Dehydrogenase 3 Family, Member A1 (ALDH3A1))

Alternative Name: ALDH3A1

Background:

Background Information: Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene Name: Aldehyde dehydrogenase 3 family, member A1

Alternative Symbols: ALDH3, ALDHIII

Protein Name: Aldehyde dehydrogenase, dimeric NADP-preferring

Molecular Weight: 50kDa

Gene ID: 218

NCBI Accession: NP_000682

UniProt: P30838