ALDH3A1 antibody (C-Term)

Catalog No. ABIN2788191

Product Details anti-ALDH3A1 Antibody

Target: ALDH3A1 (Aldehyde Dehydrogenase 3 Family, Member A1 (ALDH3A1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH3A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: KFMNSGQTCV APDYILCDPS IQNQIVEKLK KSLKEFYGED AKKSRDYGRI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ALDH3A1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ALDH3A1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 453 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ALDH3A1

Target: ALDH3A1 (Aldehyde Dehydrogenase 3 Family, Member A1 (ALDH3A1))

Alternative Name: ALDH3A1 (ALDH3A1 Products)

Synonyms: ALDC antibody, ALDH-E1 antibody, ALDH1 antibody, ALDH11 antibody, PUMB1 antibody, RALDH1 antibody, ALDH3 antibody, ALDHIII antibody, Ahd-4 antibody, Ahd4 antibody, Aldh antibody, Aldh3 antibody, AHDC antibody, Ahd-c antibody, aldehyde dehydrogenase 1 family member A1 antibody, aldehyde dehydrogenase 3 family member A1 antibody, aldehyde dehydrogenase antibody, aldehyde dehydrogenase, dimeric NADP-preferring antibody, aldehyde dehydrogenase family 3, subfamily A1 antibody, aldehyde dehydrogenase 3 family, member A1 antibody, ALDH1A1 antibody, ALDH3A1 antibody, OE_RS03630 antibody, LOC100077088 antibody, CLL_A1665 antibody, LOC100281700 antibody, LOC100285809 antibody, Aldh3a1 antibody

Background: Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Alias Symbols: ALDH3, ALDHIII, MGC10406
Protein Interaction Partner: WWOX, CYHR1, SRF, POT1, ALDH3A1,
Protein Size: 453

Molecular Weight: 50 kDa

Gene ID: 218

NCBI Accession: NM_000691, NP_000682

UniProt: P30838