GRK7 antibody (C-Term)

Catalog No. ABIN2788227

The Rabbit Polyclonal anti-GRK7 antibody (ABIN2788227) specifically detects GRK7 in WB. The antibody is reactive with Human, Cow, Dog, Guinea Pig, Horse and Rat samples.

Quick Overview for GRK7 antibody (C-Term) (ABIN2788227)

Target: GRK7 (G Protein-Coupled Receptor Kinase 7 (GRK7))

Reactivity: Human, Cow, Dog, Guinea Pig, Horse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRK7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GRK7 Antibody

Binding Specificity: C-Term

Sequence: FFKNFATGAV PIAWQEEIIE TGLFEELNDP NRPTGCEEGN SSKSGVCLLL

Predicted Reactivity: Cow: 85%, Dog: 92%, Guinea Pig: 91%, Horse: 79%, Human: 100%, Rat: 82%

Characteristics: This is a rabbit polyclonal antibody against GRK7. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GRK7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 553 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GRK7

Target: GRK7 (G Protein-Coupled Receptor Kinase 7 (GRK7))

Alternative Name: GRK7

Background: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. It is specifically expressed in the retina and the encoded protein has been shown to phosphorylate cone opsins and initiate their deactivation.
Alias Symbols: GPRK7
Protein Interaction Partner: HSP90AA1, NEDD4, PDE6D,
Protein Size: 553

Molecular Weight: 62 kDa

Gene ID: 131890

NCBI Accession: NM_139209, NP_631948

UniProt: Q8WTQ7

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction