GRK7 antibody (AA 340-420)

Catalog No. ABIN7215168

This Rabbit Polyclonal antibody specifically detects GRK7 in ELISA, WB and IF. It exhibits reactivity toward Human.

Quick Overview for GRK7 antibody (AA 340-420) (ABIN7215168)

Target: GRK7 (G Protein-Coupled Receptor Kinase 7 (GRK7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRK7 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-GRK7 Antibody

Binding Specificity: AA 340-420

Purpose: Rabbit Anti-GRK 7 Polyclonal Antibody

Specificity: GRK 7 Polyclonal Antibody detects endogenous levels of GRK 7 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human GRK 7 at AA range: 340-420

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GRK7

Target: GRK7 (G Protein-Coupled Receptor Kinase 7 (GRK7))

Alternative Name: GRK 7

Background: GRK7, GPRK7, G protein-coupled receptor kinase 7, G protein-coupled receptor kinase GRK7GRK7 encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. It is specifically expressed in the retina and G protein-coupled receptor kinase 7 has been shown to phosphorylate cone opsins and initiate their deactivation.

Molecular Weight: 62kD

Gene ID: 131890

UniProt: Q8WTQ7

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction