DNAJC2 antibody (C-Term)

Catalog No. ABIN2788243

Product Details anti-DNAJC2 Antibody

Target: DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Cow, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNAJC2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EINEQIRKEK EEAEARMRQA SKNTEKSTGG GGNGSKNWSE DDLQLLIKAV

Predicted Reactivity: Cow: 86%, Dog: 92%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against DNAJC2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DNAJC2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 621 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DNAJC2

Target: DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))

Alternative Name: DNAJC2 (DNAJC2 Products)

Synonyms: zrf1 antibody, ZRF1 antibody, MPHOSPH11 antibody, MPP11 antibody, ZUO1 antibody, AU020218 antibody, MIDA1 antibody, Zrf1 antibody, Zrf2 antibody, zgc:85671 antibody, DnaJ heat shock protein family (Hsp40) member C2 antibody, DnaJ (Hsp40) homolog, subfamily C, member 2 antibody, dnajc2 antibody, DNAJC2 antibody, Dnajc2 antibody

Background: This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.
Alias Symbols: MPHOSPH11, MPP11, ZRF1, ZUO1
Protein Interaction Partner: HIST2H2AA3, UBC, RNF2, HSPA14, HSPA8,
Protein Size: 621

Molecular Weight: 72 kDa

Gene ID: 27000

NCBI Accession: NM_014377, NP_055192

UniProt: Q99543

Pathways: Chromatin Binding