MAGEA11 antibody (Middle Region)

Catalog No. ABIN2788248

This Rabbit Polyclonal antibody specifically detects MAGEA11 in WB. It exhibits reactivity toward Human and Zebrafish (Danio rerio).

Quick Overview for MAGEA11 antibody (Middle Region) (ABIN2788248)

Target: MAGEA11 (Melanoma Antigen Family A, 11 (MAGEA11))

Reactivity: Human, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEA11 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MAGEA11 Antibody

Binding Specificity: Middle Region

Purpose: MAGEA11 Antibody - middle region

Sequence: FSSTLNVGTL EELPAAESPS PPQSPQEESF SPTAMDAIFG SLSDEGSGSQ

Predicted Reactivity: Human: 100%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against MAGEA11. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MAGEA11

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59877-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAGEA11

Target: MAGEA11 (Melanoma Antigen Family A, 11 (MAGEA11))

Alternative Name: MAGEA11

Background:

Background Information: This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: Melanoma antigen family A, 11

Alternative Symbols: CT1.11, MAGE11, MAGE-11, MAGEA-11

Protein Name: Melanoma-associated antigen 11

Molecular Weight: 48kDa

Gene ID: 4110

NCBI Accession: NP_005357

UniProt: P43364