SPANXC antibody (N-Term)

Catalog No. ABIN2788255

The Rabbit Polyclonal anti-SPANXC antibody (ABIN2788255) specifically detects SPANXC in WB. The antibody is reactive with Human samples.

Quick Overview for SPANXC antibody (N-Term) (ABIN2788255)

Target: SPANXC (SPANX Family, Member C (SPANXC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPANXC antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SPANXC Antibody

Binding Specificity: N-Term

Purpose: SPANXC Antibody - N-terminal region

Sequence: EVNETMPETP TGDSDPQPAP KKMKTSESST ILVVRYRRNV KRTSPEELLN

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against SPANXC. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59900-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SPANXC

Target: SPANXC (SPANX Family, Member C (SPANXC))

Alternative Name: SPANXC

Background:

Background Information: Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family, which is located in a gene cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a protein that localizes to the nucleus and is expressed in highly metastatic cell lines, making the protein a potential diagnostic and prognostic marker. The protein belongs to a family of cancer/testis antigens and represents a potential target for cancer immunotherapy.

Gene Name: SPANX family, member C

Alternative Symbols: CTp11, CT11.3, SPANXE, SPANX-C, SPANX-E

Protein Name: Sperm protein associated with the nucleus on the X chromosome C

Molecular Weight: 11kDa

Gene ID: 64663

NCBI Accession: NP_073152

UniProt: Q9NY87