ADD3 antibody (C-Term)

Catalog No. ABIN2788272

The Rabbit Polyclonal anti-ADD3 antibody is suitable to detect ADD3 in samples from Human, Mouse, Rat, Cow, Guinea Pig, Dog, Horse, Rabbit and Zebrafish (Danio rerio). It has been validated for WB and IF.

Quick Overview for ADD3 antibody (C-Term) (ABIN2788272)

Target: ADD3 (Adducin 3 (Gamma) (ADD3))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Dog, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADD3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-ADD3 Antibody

Binding Specificity: C-Term

Purpose: ADD3 Antibody - C-terminal region

Sequence: DELAKRVSRL STSTTIENIE ITIKSPEKIE EVLSPEGSPS KSPSKKKKKF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against ADD3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ADD3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59946-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ADD3

Target: ADD3 (Adducin 3 (Gamma) (ADD3))

Alternative Name: ADD3

Background:

Background Information: Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains.

Gene Name: Adducin 3 (gamma)

Alternative Symbols: ADDL, CPSQ3

Protein Name: Gamma-adducin

Molecular Weight: 78kDa

Gene ID: 120

NCBI Accession: NP_001112

UniProt: Q9UEY8