ADORA1 antibody (C-Term)

Catalog No. ABIN2788275

This Rabbit Polyclonal antibody specifically detects ADORA1 in WB. It exhibits reactivity toward Human, Rat, Mouse, Dog, Cow, Guinea Pig, Horse and Rabbit.

Quick Overview for ADORA1 antibody (C-Term) (ABIN2788275)

Target: ADORA1 (Adenosine A1 Receptor (ADORA1))

Reactivity: Human, Rat, Mouse, Dog, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADORA1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ADORA1 Antibody

Binding Specificity: C-Term

Sequence: VLPPLLLMVL IYLEVFYLIR KQLNKKVSAS SGDPQKYYGK ELKIAKSLAL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ADORA1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ADORA1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 326 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ADORA1

Target: ADORA1 (Adenosine A1 Receptor (ADORA1))

Alternative Name: ADORA1

Background: The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene.
Alias Symbols: RDC7
Protein Interaction Partner: SNF8, ATXN1L, EPB41L2, GRM1, P2RY1, GNAI2, GNAS, GNAO1, GNAZ, DRD1, ADA,
Protein Size: 326

Molecular Weight: 36 kDa

Gene ID: 134

NCBI Accession: NM_000674, NP_000665

UniProt: P30542

Pathways: EGFR Signaling Pathway, Negative Regulation of Hormone Secretion, Synaptic Membrane