Adenosine A2a Receptor antibody (C-Term)

Catalog No. ABIN2788276

Product Details anti-Adenosine A2a Receptor Antibody

Target: Adenosine A2a Receptor (ADORA2A)

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Guinea Pig, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adenosine A2a Receptor antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MESQPLPGER ARSTLQKEVH AAKSLAIIVG LFALCWLPLH IINCFTFFCP

Predicted Reactivity: Cow: 80%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ADORA2A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ADORA2A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 412 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Adenosine A2a Receptor

Target: Adenosine A2a Receptor (ADORA2A)

Alternative Name: ADORA2A (ADORA2A Products)

Synonyms: ADORA2A antibody, adora2a.1 antibody, zgc:194773 antibody, A2aR antibody, ADORA2 antibody, RDC8 antibody, A2AAR antibody, AA2AR antibody, A2ar antibody, ADENO antibody, Adora2l1 antibody, adora2a.2 antibody, zgc:193802 antibody, zgc:193822 antibody, adenosine A2a receptor antibody, adenosine A2a receptor a antibody, adenosine A2a receptor L homeolog antibody, adenosine A2a receptor b antibody, ADORA2A antibody, Adora2a antibody, adora2aa antibody, adora2a.L antibody, adora2a antibody, adora2ab antibody

Background: ADORA2A is one of several receptor subtypes for adenosine. The activity of the protein, a G-protein coupled receptor family member, is mediated by G proteins which activate adenylyl cyclase. ADORA2A is abundant in basal ganglia, vasculature and platelets and it is a major target of caffeine.
Alias Symbols: ADORA2, RDC8, hA2aR
Protein Interaction Partner: NAMPT, Actn1, Actn4, Actn3, Actn2, ADORA2A, CYTH2, DRD2, ADA,
Protein Size: 412

Molecular Weight: 45 kDa

Gene ID: 135

NCBI Accession: NM_000675, NP_000666

UniProt: P29274

Pathways: Neurotrophin Signaling Pathway, cAMP Metabolic Process, Synaptic Membrane, Feeding Behaviour, Cancer Immune Checkpoints