Adenosine A2a Receptor antibody (C-Term)

Catalog No. ABIN2788276

The Rabbit Polyclonal anti-Adenosine A2a Receptor antibody is suitable to detect Adenosine A2a Receptor in samples from Human, Mouse, Rat, Dog, Rabbit, Guinea Pig, Cow and Horse. It has been validated for WB and IHC.

Quick Overview for Adenosine A2a Receptor antibody (C-Term) (ABIN2788276)

Target: Adenosine A2a Receptor (ADORA2A)

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Guinea Pig, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adenosine A2a Receptor antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Adenosine A2a Receptor Antibody

Binding Specificity: C-Term

Purpose: ADORA2A Antibody - C-terminal region

Sequence: MESQPLPGER ARSTLQKEVH AAKSLAIIVG LFALCWLPLH IINCFTFFCP

Predicted Reactivity: Cow: 80%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ADORA2A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ADORA2A

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59953-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Adenosine A2a Receptor

Target: Adenosine A2a Receptor (ADORA2A)

Alternative Name: ADORA2A

Background:

Background Information: ADORA2A is one of several receptor subtypes for adenosine. The activity of the protein, a G-protein coupled receptor family member, is mediated by G proteins which activate adenylyl cyclase. ADORA2A is abundant in basal ganglia, vasculature and platelets and it is a major target of caffeine.

Gene Name: Adenosine A2a receptor

Alternative Symbols: A2aR, RDC8, ADORA2

Protein Name: Adenosine receptor A2a

Molecular Weight: 45kDa

Gene ID: 135

NCBI Accession: NP_000666

UniProt: P29274

Pathways: Neurotrophin Signaling Pathway, cAMP Metabolic Process, Synaptic Membrane, Feeding Behaviour, Cancer Immune Checkpoints