Adenosine A2b Receptor antibody (C-Term)

Catalog No. ABIN2788277

The Rabbit Polyclonal anti-Adenosine A2b Receptor antibody is suitable to detect Adenosine A2b Receptor in samples from Human, Guinea Pig, Dog, Horse and Rabbit. It has been validated for WB.

Quick Overview for Adenosine A2b Receptor antibody (C-Term) (ABIN2788277)

Target: Adenosine A2b Receptor (ADORA2B)

Reactivity: Human, Guinea Pig, Dog, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adenosine A2b Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Adenosine A2b Receptor Antibody

Binding Specificity: C-Term

Purpose: ADORA2B Antibody - C-terminal region

Sequence: AKSLAMIVGI FALCWLPVHA VNCVTLFQPA QGKNKPKWAM NMAILLSHAN

Predicted Reactivity: Dog: 79%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Rabbit: 86%

Characteristics: This is a rabbit polyclonal antibody against ADORA2B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ADORA2B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59954-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Adenosine A2b Receptor

Target: Adenosine A2b Receptor (ADORA2B)

Alternative Name: ADORA2B

Background:

Background Information: This gene encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. This protein also interacts with netrin-1, which is involved in axon elongation. The gene is located near the Smith-Magenis syndrome region on chromosome 17.

Gene Name: Adenosine A2b receptor

Alternative Symbols: ADORA2

Protein Name: Adenosine receptor A2b

Molecular Weight: 36kDa

Gene ID: 136

NCBI Accession: NP_000667

UniProt: P29275

Pathways: cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process