alpha 1 Adrenergic Receptor antibody (C-Term)

Catalog No. ABIN2788283

The Rabbit Polyclonal anti-alpha 1 Adrenergic Receptor antibody is suitable to detect alpha 1 Adrenergic Receptor in samples from Human, Mouse, Rat, Cow, Rabbit, Dog, Horse, Sheep and Guinea Pig. It has been validated for WB.

Quick Overview for alpha 1 Adrenergic Receptor antibody (C-Term) (ABIN2788283)

Target: alpha 1 Adrenergic Receptor (ADRA1A) (Adrenoceptor alpha 1A (ADRA1A))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Horse, Sheep, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This alpha 1 Adrenergic Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-alpha 1 Adrenergic Receptor Antibody

Binding Specificity: C-Term

Sequence: LKSGLKTDKS DSEQVTLRIH RKNAPAGGSG MASAKTKTHF SVRLLKFSRE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against ADRA1A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ADRA1A

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for alpha 1 Adrenergic Receptor

Target: alpha 1 Adrenergic Receptor (ADRA1A) (Adrenoceptor alpha 1A (ADRA1A))

Alternative Name: ADRA1A

Background: Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties.
Alias Symbols: ADRA1C, ADRA1L1, ALPHA1AAR
Protein Interaction Partner: PPP1R9B, RGS2, ABR, NOS1, CXCR1, CXCR2, BMP1, ADRA1B, ADRA1D, FLNC,
Protein Size: 370

Molecular Weight: 40 kDa

Gene ID: 148

NCBI Accession: NM_033304, NP_150647

Pathways: AMPK Signaling