CLTB antibody (C-Term)

Catalog No. ABIN2788294

This Rabbit Polyclonal antibody specifically detects CLTB in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Rabbit and Guinea Pig.

Quick Overview for CLTB antibody (C-Term) (ABIN2788294)

Target: CLTB (Clathrin, Light Chain B (CLTB))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLTB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CLTB Antibody

Binding Specificity: C-Term

Sequence: ADIIGYVASE EAFVKESKEE TPGTEWEKVA QLCDFNPKSS KQCKDVSRLR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CLTB. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CLTB

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 229 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CLTB

Target: CLTB (Clathrin, Light Chain B (CLTB))

Alternative Name: CLTB

Background: Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants.
Alias Symbols: LCB
Protein Interaction Partner: TP53, UBC, MDM2, PAN2, FN1, ARRB2, HIP1R, HIP1, PQBP1, CLTC, CSNK2A2, CSNK2A1, CALM1,
Protein Size: 229

Molecular Weight: 25 kDa

Gene ID: 1212

NCBI Accession: NM_007097, NP_009028

UniProt: P09497

Pathways: Synaptic Membrane