Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants.
Alias Symbols: LCB
Protein Interaction Partner: TP53, UBC, MDM2, PAN2, FN1, ARRB2, HIP1R, HIP1, PQBP1, CLTC, CSNK2A2, CSNK2A1, CALM1,
Protein Size: 229