CNR1 antibody (N-Term)

Catalog No. ABIN2788297

The Rabbit Polyclonal anti-CNR1 antibody is suitable to detect CNR1 in samples from Human, Rat, Mouse, Dog, Cow, Horse, Guinea Pig and Rabbit. It has been validated for WB.

Quick Overview for CNR1 antibody (N-Term) (ABIN2788297)

Target: CNR1 (Cannabinoid Receptor 1 (CNR1))

Reactivity: Human, Rat, Mouse, Dog, Cow, Horse, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CNR1 Antibody

Binding Specificity: N-Term

Purpose: CNR1 Antibody - N-terminal region

Sequence: ADQVNITEFY NKSLSSFKEN EENIQCGENF MDIECFMVLN PSQQLAIAVL

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CNR1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CNR1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59994-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CNR1

Target: CNR1 (Cannabinoid Receptor 1 (CNR1))

Alternative Name: CNR1

Background:

Background Information: This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana.

Gene Name: Cannabinoid receptor 1 (brain)

Alternative Symbols: CB1, CNR, CB-R, CB1A, CB1R, CANN6, CB1K5

Protein Name: Cannabinoid receptor 1

Molecular Weight: 45kDa

Gene ID: 1268

NCBI Accession: NP_057167

UniProt: P21554

Pathways: Feeding Behaviour