ETFDH antibody (C-Term)

Catalog No. ABIN2788312

The Rabbit Polyclonal anti-ETFDH antibody is suitable to detect ETFDH in samples from Human, Pig, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig and Horse. It has been validated for WB.

Quick Overview for ETFDH antibody (C-Term) (ABIN2788312)

Target: ETFDH (Electron-Transferring-Flavoprotein Dehydrogenase (ETFDH))

Reactivity: Human, Pig, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ETFDH antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ETFDH Antibody

Binding Specificity: C-Term

Purpose: ETFDH Antibody - C-terminal region

Sequence: KTIGLHVTEY EDNLKNSWVW KELYSVRNIR PSCHGVLGVY GGMIYTGIFY

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ETFDH. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ETFDH

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60030-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ETFDH

Target: ETFDH (Electron-Transferring-Flavoprotein Dehydrogenase (ETFDH))

Alternative Name: ETFDH

Background:

Background Information: Electron-transferring-flavoprotein dehydrogenase in the inner mitochondrial membrane accepts electrons from electron-transfer flavoprotein which is located in the mitochondrial matrix and reduces ubiquinone in the mitochondrial membrane. The protein is synthesized as a 67- kDa precursor which is targeted to mitochondria and processed in a single step to a 64- kDa mature form located in the mitochondrial membrane. Deficiency in electron-transferring-flavoprotein dehydrogenase have been demonstrated in some patients with type II glutaricacidemia

Alternative Symbols: MADD, ETFQO

Protein Name: Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial

Molecular Weight: 65kDa

Gene ID: 2110

NCBI Accession: NP_004444

UniProt: Q16134

Pathways: Monocarboxylic Acid Catabolic Process