F2RL2 antibody (C-Term)

Catalog No. ABIN2788315

The Rabbit Polyclonal anti-F2RL2 antibody has been validated for WB. It is suitable to detect F2RL2 in samples from Human, Cow and Pig.

Quick Overview for F2RL2 antibody (C-Term) (ABIN2788315)

Target: F2RL2 (Coagulation Factor II (thrombin) Receptor-Like 2 (F2RL2))

Reactivity: Human, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This F2RL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-F2RL2 Antibody

Binding Specificity: C-Term

Sequence: HANYYYNNTD GLYFIYLIAL CLGSLNSCLD PFLYFLMSKT RNHSTAYLTK

Predicted Reactivity: Cow: 77%, Human: 100%, Pig: 77%

Characteristics: This is a rabbit polyclonal antibody against F2RL2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human F2RL2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 374 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for F2RL2

Target: F2RL2 (Coagulation Factor II (thrombin) Receptor-Like 2 (F2RL2))

Alternative Name: F2RL2

Background: Coagulation factor II (thrombin) receptor-like 2 (F2RL2) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL2 is also a member of the protease-activated receptor family and activated by thrombin. F2RL2 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL2 is a cofactor for F2RL3 activation by thrombin. It mediates thrombin-triggered phosphoinositide hydrolysis and is expressed in a variety of tissues.
Alias Symbols: PAR3, PAR-3
Protein Interaction Partner: UBC, F11R, ECT2, JAM3, JAM2, F2RL3, CDH5, F2, CTSG,
Protein Size: 374

Molecular Weight: 42 kDa

Gene ID: 2151

NCBI Accession: NM_004101, NP_004092

UniProt: O00254

Pathways: Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling