C1QA antibody (N-Term)

Catalog No. ABIN2788322

The Rabbit Polyclonal anti-C1QA antibody is suitable to detect C1QA in samples from Human, Mouse, Rat, Cow, Dog, Horse, Pig and Rabbit. It has been validated for WB.

Quick Overview for C1QA antibody (N-Term) (ABIN2788322)

Target: C1QA (Complement Component 1, Q Subcomponent, A Chain (C1QA))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1QA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-C1QA Antibody

Binding Specificity: N-Term

Purpose: C1QA Antibody - N-terminal region

Sequence: PGKVGYPGPS GPLGARGIPG IKGTKGSPGN IKDQPRPAFS AIRRNPPMGG

Predicted Reactivity: Cow: 100%, Dog: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 85%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against C1QA. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human C1QA

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60064-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for C1QA

Target: C1QA (Complement Component 1, Q Subcomponent, A Chain (C1QA))

Alternative Name: C1QA

Background:

Targeted Subunit: A

Background Information: This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the A-chain polypeptide of human complement subcomponent C1q.

Gene Name: Complement component 1, q subcomponent, A chain

Alternative Symbols: -

Protein Name: Complement C1q subcomponent subunit A

Molecular Weight: 26 kDa

Gene ID: 712

NCBI Accession: NP_057075

UniProt: P02745

Pathways: Complement System