CA5A antibody (C-Term)

Catalog No. ABIN2788330

The Rabbit Polyclonal anti-CA5A antibody is suitable to detect CA5A in samples from Human. It has been validated for WB.

Quick Overview for CA5A antibody (C-Term) (ABIN2788330)

Target: CA5A (Carbonic Anhydrase VA (CA5A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CA5A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CA5A Antibody

Binding Specificity: C-Term

Purpose: CA5A Antibody - C-terminal region

Sequence: PSQLSAFRTL LFSALGEEEK MMVNNYRPLQ PLMNRKVWAS FQATNEGTRS

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against CA5A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CA5A

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60096-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CA5A

Target: CA5A (Carbonic Anhydrase VA (CA5A))

Alternative Name: CA5A

Background:

Background Information: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VA is localized in the mitochondria and expressed primarily in the liver. It may play an important role in ureagenesis and gluconeogenesis. CA5A gene maps to chromosome 16q24.3 and an unprocessed pseudogene has been assigned to 16p12-p11.2.

Gene Name: Carbonic anhydrase VA, mitochondrial

Alternative Symbols: CA5, CAV, CAVA, CA5AD, GS1-21A4.1

Protein Name: Carbonic anhydrase 5A, mitochondrial

Molecular Weight: 34kDa

Gene ID: 763

NCBI Accession: NP_001730

UniProt: P35218