RND3 antibody (C-Term)

Catalog No. ABIN2788363

The Rabbit Polyclonal anti-RND3 antibody is suitable to detect RND3 in samples from Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for RND3 antibody (C-Term) (ABIN2788363)

Target: RND3 (rho Family GTPase 3 (RND3))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RND3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RND3 Antibody

Binding Specificity: C-Term

Sequence: TLACVNKTNK NVKRNKSQRA TKRISHMPSR PELSAVATDL RKDKAKSCTV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against RND3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human RND3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RND3

Target: RND3 (rho Family GTPase 3 (RND3))

Alternative Name: RND3

Background: This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Alias Symbols: ARHE, Rho8, RhoE, memB
Protein Interaction Partner: UBC, SKP2, PLEKHG5, RGS14, PLXNB1, ARHGAP35, UBXN11, ARHGAP5, ROCK1, CIT, SFN,
Protein Size: 244

Molecular Weight: 27 kDa

Gene ID: 390

NCBI Accession: NM_005168, NP_005159

UniProt: P61587