OSBP antibody (C-Term)

Catalog No. ABIN2788369

The Rabbit Polyclonal anti-OSBP antibody has been validated for WB and IHC. It is suitable to detect OSBP in samples from Human, Mouse, Rat, Rabbit, Dog, Cow, Guinea Pig, Horse and Zebrafish (Danio rerio).

Quick Overview for OSBP antibody (C-Term) (ABIN2788369)

Target: OSBP (Oxysterol Binding Protein (OSBP))

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OSBP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-OSBP Antibody

Binding Specificity: C-Term

Sequence: ALTLNAWESG TAPTDSRLRP DQRLMENGRW DEANAEKQRL EEKQRLSRKK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against OSBP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human OSBP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 807 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for OSBP

Target: OSBP (Oxysterol Binding Protein (OSBP))

Alternative Name: OSBP

Background: Oxysterol binding protein is an intracellular protein that is believed to transport sterols from lysosomes to the nucleus where the sterol down-regulates the genes for the LDL receptor, HMG-CoA reductase, and HMG synthetase .
Alias Symbols: OSBP1
Protein Interaction Partner: VAPB, FKBP6, UBC, SUMO1, KCTD12, TBC1D17, CORO1B, CAND1, PARVA, SAMHD1, SWAP70, XPO7, SEC23A, PRMT3, ZRANB2, HIST1H4A, USP11, SF1, TTC1, NPM1, NARS, NAP1L1, GFPT1, GARS, EIF4B, CTNNA1, CSNK2A1, ELAVL1, RAD21, VAPA,
Protein Size: 807

Molecular Weight: 89 kDa

Gene ID: 5007

NCBI Accession: NM_002556, NP_002547

UniProt: P22059