BCAM antibody (C-Term)

Catalog No. ABIN2788375

Product Details anti-BCAM Antibody

Target: BCAM (Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))

Binding Specificity: C-Term

Reactivity: Human, Cow, Dog, Rabbit, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCAM antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SALSRDGISC EASNPHGNKR HVFHFGTVSP QTSQAGVAVM AVAVSVGLLL

Predicted Reactivity: Cow: 79%, Dog: 86%, Horse: 93%, Human: 100%, Pig: 93%, Rabbit: 86%

Characteristics: This is a rabbit polyclonal antibody against BCAM. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human BCAM

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 628 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BCAM

Target: BCAM (Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))

Alternative Name: BCAM (BCAM Products)

Background: Lutheran blood group glycoprotein is a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five, N-terminus, extracellular immunoglobulin domains, a single transmembrane domain, and a short, C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: AU, CD239, LU, MSK19
Protein Interaction Partner: KLHL2, SUMO1, UBE2I, UBC, LAMA5, EPB41,
Protein Size: 628

Molecular Weight: 64 kDa

Gene ID: 4059

NCBI Accession: NM_005581, NP_005572

UniProt: P50895