LOXL3 antibody (Middle Region)

Catalog No. ABIN2788388

Product Details anti-LOXL3 Antibody

Target: LOXL3 (Lysyl Oxidase-Like 3 (LOXL3))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LOXL3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AASSGQKKQQ QSKPQGEARV RLKGGAHPGE GRVEVLKAST WGTVCDRKWD

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against LOXL3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LOXL3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 753 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LOXL3

Target: LOXL3 (Lysyl Oxidase-Like 3 (LOXL3))

Alternative Name: LOXL3 (LOXL3 Products)

Synonyms: LOXL antibody, Lor2 antibody, Loxl2 antibody, LOXL3 antibody, loxl-3 antibody, fj60c12 antibody, im:7157119 antibody, loxl3 antibody, wu:fj60c12 antibody, zgc:162959 antibody, lysyl oxidase like 3 antibody, lysyl oxidase-like 3 antibody, lysyl oxidase like 3 S homeolog antibody, lysyl oxidase-like 3b antibody, LOXL3 antibody, Loxl3 antibody, loxl3.S antibody, loxl3b antibody

Background: LOXL3 is a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
Alias Symbols: LOXL
Protein Interaction Partner: APMAP,
Protein Size: 753

Molecular Weight: 80 kDa

Gene ID: 84695

NCBI Accession: NM_032603, NP_115992

UniProt: P58215