LTBP1 antibody (C-Term)

Catalog No. ABIN2788392

The Rabbit Polyclonal anti-LTBP1 antibody (ABIN2788392) specifically detects LTBP1 in WB. The antibody is reactive with Mouse, Human, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit samples.

Quick Overview for LTBP1 antibody (C-Term) (ABIN2788392)

Target: LTBP1 (Latent Transforming Growth Factor beta Binding Protein 1 (LTBP1))

Reactivity: Mouse, Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LTBP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LTBP1 Antibody

Binding Specificity: C-Term

Sequence: NVCANGDCSN LEGSYMCSCH KGYTRTPDHK HCRDIDECQQ GNLCVNGQCK

Predicted Reactivity: Cow: 92%, Dog: 92%, Guinea Pig: 83%, Horse: 86%, Human: 100%, Mouse: 83%, Rabbit: 92%, Rat: 83%

Characteristics: This is a rabbit polyclonal antibody against LTBP1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human LTBP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1396 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LTBP1

Target: LTBP1 (Latent Transforming Growth Factor beta Binding Protein 1 (LTBP1))

Alternative Name: LTBP1

Background: The protein encoded by this gene belongs to the family of latent TGF-beta binding proteins (LTBPs). The secretion and activation of TGF-betas is regulated by their association with latency-associated proteins and with latent TGF-beta binding proteins. The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent cytokine is subsequently activated by several different mechanisms.
Alias Symbols: MGC163161
Protein Interaction Partner: FBXO6, SMURF1, ATN1, CACNA1A, TGM2, LTBP1, ITGB5, IGFBP3, FN1, FBN1, FBN2, TGFB1,
Protein Size: 1396

Molecular Weight: 154 kDa

Gene ID: 4052

NCBI Accession: NM_000627, NP_000618

Pathways: Maintenance of Protein Location, Growth Factor Binding