MCEE antibody (C-Term)

Catalog No. ABIN2788409

This Rabbit Polyclonal antibody specifically detects MCEE in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Horse, Pig, Rabbit, Zebrafish (Danio rerio), Cow and Guinea Pig.

Quick Overview for MCEE antibody (C-Term) (ABIN2788409)

Target: MCEE (Methylmalonyl CoA Epimerase (MCEE))

Reactivity: Human, Mouse, Rat, Dog, Horse, Pig, Rabbit, Zebrafish (Danio rerio), Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCEE antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MCEE Antibody

Binding Specificity: C-Term

Purpose: MCEE Antibody - C-terminal region

Sequence: DSPIAGFLQK NKAGGMHHIC IEVDNINAAV MDLKKKKIRS LSEEVKIGAH

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against MCEE. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MCEE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60330-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MCEE

Target: MCEE (Methylmalonyl CoA Epimerase (MCEE))

Alternative Name: MCEE

Background:

Background Information: MCEE catalyzes the interconversion of D- and L-methylmalonyl-CoA during the degradation of branched chain amino acids. odd chain-length fatty acids, and other metabolites. Mutations in this gene result in methylmalonyl-CoA epimerase deficiency, which is presented as mild to moderate methylmalonic aciduria.

Gene Name: Methylmalonyl CoA epimerase

Alternative Symbols: MCE, GLOD2

Protein Name: Methylmalonyl-CoA epimerase, mitochondrial

Molecular Weight: 19kDa

Gene ID: 84693

NCBI Accession: NP_115990

UniProt: Q96PE7

Pathways: Monocarboxylic Acid Catabolic Process