MKNK1 antibody (N-Term)

Catalog No. ABIN2788414

This anti-MKNK1 antibody is a Rabbit Polyclonal antibody detecting MKNK1 in WB. Suitable for Human, Mouse, Rat, Cow, Horse, Dog, Guinea Pig and Rabbit.

Quick Overview for MKNK1 antibody (N-Term) (ABIN2788414)

Target: MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))

Reactivity: Human, Mouse, Rat, Cow, Horse, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MKNK1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MKNK1 Antibody

Binding Specificity: N-Term

Sequence: CQGNKNILEL IEFFEDDTRF YLVFEKLQGG SILAHIQKQK HFNEREASRV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MKNK1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MKNK1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 465 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MKNK1

Target: MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))

Alternative Name: MKNK1

Background: MKNK1 may play a role in the response to environmental stress and cytokines. It appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.
Alias Symbols: MNK1
Protein Interaction Partner: MAPK11, MAPK14, TNIP2, RCN3, HIPK2, HGS, APP, SPRY2, ATXN3, PHAX, DDAH2, EIF4G3, UBE2D1, DNAJC7, PRKDC, HSP90AB1, CREBBP, MKNK1, EIF4G2, PLA2G4A, EIF4G1, PAK2, MAPK3, MAPK1, MBP, EIF4E, FANCA,
Protein Size: 465

Molecular Weight: 51 kDa

Gene ID: 8569

NCBI Accession: NM_003684, NP_003675

UniProt: Q9BUB5

Pathways: MAPK Signaling, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor