ST5 antibody (Middle Region)
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- Target See all ST5 Antibodies
- ST5 (Suppression of Tumorigenicity 5 (ST5))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Guinea Pig, Horse, Rabbit, Cow, Dog
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ST5 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- VPKPKRTFEY EADKNPKSKP SNGLPPSPTP AAPPPLPSTP APPVTRRPKK
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against ST5. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human ST5
- Top Product
- Discover our top product ST5 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 1137 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ST5 (Suppression of Tumorigenicity 5 (ST5))
- Alternative Name
- ST5 (ST5 Products)
- Synonyms
- zgc:91902 antibody, wu:fc11b09 antibody, si:ch211-208c6.1 antibody, ST5 antibody, DKFZp459D1230 antibody, hts1 antibody, p126 antibody, dennd2b antibody, DENND2B antibody, HTS1 antibody, 2010004M01Rik antibody, 2610305K15Rik antibody, suppression of tumorigenicity 5 antibody, st5 antibody, ST5 antibody, St5 antibody
- Background
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This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.
Alias Symbols: DENND2B, HTS1, MGC33090, p126
Protein Interaction Partner: SMAD2, UBC, ABL1, SFN,
Protein Size: 1137 - Molecular Weight
- 126 kDa
- Gene ID
- 6764
- NCBI Accession
- NM_005418, NP_005409
- UniProt
- P78524
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