MRI1 antibody (N-Term)

Catalog No. ABIN2788458

The Rabbit Polyclonal anti-MRI1 antibody is suitable to detect MRI1 in samples from Human, Rabbit, Dog, Cow and Guinea Pig. It has been validated for WB.

Quick Overview for MRI1 antibody (N-Term) (ABIN2788458)

Target: MRI1 (Mri1) (Methylthioribose-1-Phosphate Isomerase 1 (Mri1))

Reactivity: Human, Rabbit, Dog, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRI1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MRI1 Antibody

Binding Specificity: N-Term

Purpose: MGC3207 Antibody - N-terminal region

Sequence: VNMARAARDL ADVAAREAER EGATEEAVRE RRETELCEHW EEHTRQRELP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Rabbit: 100%

Characteristics: This is a rabbit polyclonal antibody against MGC3207. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MGC3207

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60474-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRI1

Target: MRI1 (Mri1) (Methylthioribose-1-Phosphate Isomerase 1 (Mri1))

Background:

Background Information: MGC3207 catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Independently from catalytic activity, MGC3207 promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.

Gene Name: Methylthioribose-1-phosphate isomerase homolog (S. cerevisiae)

Alternative Symbols: M1Pi, MRDI, MTNA, Ypr118w

Protein Name: Methylthioribose-1-phosphate isomerase

Molecular Weight: 34kDa

Gene ID: 84245

NCBI Accession: NP_115661

UniProt: Q9BV20

Pathways: Methionine Biosynthetic Process