MRPL45 antibody (C-Term)

Catalog No. ABIN2788461

The Rabbit Polyclonal anti-MRPL45 antibody has been validated for WB. It is suitable to detect MRPL45 in samples from Human, Mouse, Rat, Cow, Guinea Pig, Dog, Horse and Rabbit.

Quick Overview for MRPL45 antibody (C-Term) (ABIN2788461)

Target: MRPL45 (Mitochondrial Ribosomal Protein L45 (MRPL45))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Dog, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL45 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MRPL45 Antibody

Binding Specificity: C-Term

Sequence: RFGRLMYGQE DVPKDVLEYV VFEKQLTNPY GSWRMHTKIV PPWAPPKQPI

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MRPL45. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MRPL45

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 306 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPL45

Target: MRPL45 (Mitochondrial Ribosomal Protein L45 (MRPL45))

Alternative Name: MRPL45

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 2p and 17q.
Alias Symbols: MGC11321, L45mt, MRP-L45
Protein Interaction Partner: TRIM23, UBC, C1QBP, TMEM177, MRPL24, MARCKSL1, MRPL9, MRPL11, MRPL32, MRPL38, MRPL47, SYNJ2BP, MRPL50, MRPL51, MRPL37, MRPL15, MRPL13, ZC3H4, HNRNPR, MRPL19, SDHB, ILF3, CUL3, ICT1, KBTBD7, G3BP1,
Protein Size: 306

Molecular Weight: 35 kDa

Gene ID: 84311

NCBI Accession: NM_032351, NP_115727

UniProt: Q9BRJ2