TNFSF13 antibody (Middle Region)

Catalog No. ABIN2788639

The Rabbit Polyclonal anti-TNFSF13 antibody is suitable to detect TNFSF13 in samples from Human, Rat, Dog, Cow, Pig, Horse, Rabbit and Goat. It has been validated for WB.

Quick Overview for TNFSF13 antibody (Middle Region) (ABIN2788639)

Target: TNFSF13 (Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13))

Reactivity: Human, Rat, Dog, Cow, Pig, Horse, Rabbit, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFSF13 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TNFSF13 Antibody

Binding Specificity: Middle Region

Sequence: EQSSDALEAW ENGERSRKRR AVLTQKQKKQ HSVLHLVPIN ATSKDDSDVT

Predicted Reactivity: Cow: 91%, Dog: 86%, Goat: 79%, Horse: 86%, Human: 100%, Pig: 93%, Rabbit: 79%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against TNFSF13. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 250 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TNFSF13

Target: TNFSF13 (Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13))

Alternative Name: TNFSF13

Background: The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified, such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.
Alias Symbols: APRIL, CD256, TALL2, TRDL-1, UNQ383/PRO715, ligand, ZTNF2, TALL-2
Protein Interaction Partner: CAMK1D, TNFRSF13B, TNFSF13B, TNFRSF14, TNFRSF11B, TNFRSF1A, SDC2, FURIN, FAS, TNFRSF17, TNFSF13,
Protein Size: 250

Molecular Weight: 16 kDa

Gene ID: 8741

NCBI Accession: NM_003808, NP_003799

UniProt: O75888

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response