Cytochrome C antibody (N-Term)

Catalog No. ABIN2788640

This anti-Cytochrome C antibody is a Rabbit Polyclonal antibody detecting Cytochrome C in WB and IF. Suitable for Human, Rat, Mouse, Horse, Dog, Rabbit, Pig, Cow, Sheep and Goat.

Quick Overview for Cytochrome C antibody (N-Term) (ABIN2788640)

Target: Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

Reactivity: Human, Rat, Mouse, Horse, Dog, Rabbit, Pig, Cow, Sheep, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cytochrome C antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Cytochrome C Antibody

Binding Specificity: N-Term

Sequence: IFIMKCSQCH TVEKGGKHKT GPNLHGLFGR KTGQAPGYSY TAANKNKGII

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against CYCS. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 105 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Cytochrome C

Target: Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

Alternative Name: CYCS

Background: This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome.
Alias Symbols: CYC, HCS, THC4
Protein Interaction Partner: KRT40, BAX, UBC, HECW2, ITGA4, ARL2, PRDX2, AGTPBP1, CDK2, SUMO2, COX4I2, NDOR1, HSPB1, CYB5R3, CYB5A, HSPA8, CYB5R1, RNF7, SAFB, CASP9, APAF1, BCL2L1, VDAC2, UQCRC1, SNCA, BCL2, CYC1, FDX1, VDAC1, GSTK1,
Protein Size: 105

Molecular Weight: 12 kDa

Gene ID: 54205

NCBI Accession: NM_018947, NP_061820

UniProt: P99999

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity