VEGFA antibody (C-Term)

Catalog No. ABIN2788641

This Rabbit Polyclonal antibody specifically detects VEGFA in WB and IHC. It exhibits reactivity toward Human, Rat, Mouse, Dog, Rabbit, Cow, Horse, Sheep and Guinea Pig.

Quick Overview for VEGFA antibody (C-Term) (ABIN2788641)

Target: VEGFA (Vascular Endothelial Growth Factor A (VEGFA))

Reactivity: Human, Rat, Mouse, Dog, Rabbit, Cow, Horse, Sheep, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VEGFA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-VEGFA Antibody

Binding Specificity: C-Term

Sequence: SFLQHNKCEC RPKKDRARQE KKSVRGKGKG QKRKRKKSRY KSWSVCDKPR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against VEGFA. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 351 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for VEGFA

Target: VEGFA (Vascular Endothelial Growth Factor A (VEGFA))

Alternative Name: VEGFA

Background: This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome.
Alias Symbols: MGC70609, MVCD1, VEGF, VPF
Protein Interaction Partner: ILF3, HNRNPL, NRP1, FLT1, LYVE1, KDR, PRRG4, VPS35, U2AF1, Flt4, ELAVL1, CRYAB, HNRNPD, HGS, UBC, HSP90AA1, HSPA4, YBX3, ADAMTS1, IGFBP7, NRP2, VEGFB, SEMA3F, PGF, EPHB2, TNXB, GPC1, VTN, VEGFA, SPARC, AKT1, YBX1, CTGF, RB1, HIF1A,
Protein Size: 351

Molecular Weight: 40 kDa

Gene ID: 7422

NCBI Accession: NM_001204385, NP_001191314

UniProt: P15692

Pathways: RTK Signaling, Glycosaminoglycan Metabolic Process, Regulation of Cell Size, Tube Formation, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling