HSP70 1A antibody (N-Term)

Catalog No. ABIN2788649

This Rabbit Polyclonal antibody specifically detects HSP70 1A in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Goat, Zebrafish (Danio rerio) and Saccharomyces cerevisiae.

Quick Overview for HSP70 1A antibody (N-Term) (ABIN2788649)

Target: HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

Reactivity: Human, Mouse, Rat, Dog, Goat, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSP70 1A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HSP70 1A Antibody

Binding Specificity: N-Term

Purpose: Hspa1a Antibody - N-terminal region

Sequence: KMKEIAEAYL GHPVTNAVIT VPAYFNDSQR QATKDAGVIA GLNVLRIINE

Predicted Reactivity: Dog: 100%, Goat: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against Hspa1a. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61005-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HSP70 1A

Target: HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

Alternative Name: Hspa1a

Background:

Background Information: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.

Gene Name: Heat shock protein 1A

Alternative Symbols: Hsp, Hsp7, Hsp70, Hsp72, hsp68, Hsp70-3, Hsp70.3, hsp70A1

Protein Name: Heat shock 70 kDa protein 1A

Molecular Weight: 70kDa

Gene ID: 193740

NCBI Accession: NP_034609

UniProt: Q61696

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process