LHCGR antibody (C-Term)

Catalog No. ABIN2788657

The Rabbit Polyclonal anti-LHCGR antibody (ABIN2788657) specifically detects LHCGR in WB. The antibody is reactive with Human, Rat, Cow, Pig, Dog, Goat, Guinea Pig, Horse and Rabbit samples.

Quick Overview for LHCGR antibody (C-Term) (ABIN2788657)

Target: LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))

Reactivity: Human, Rat, Cow, Pig, Dog, Goat, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LHCGR antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LHCGR Antibody

Binding Specificity: C-Term

Sequence: LLLSKFGCCK RRAELYRRKD FSAYTSNCKN GFTGSNKPSQ STLKLSTLHC

Predicted Reactivity: Cow: 93%, Dog: 100%, Goat: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Pig: 93%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against LHCGR. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human LHCGR

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LHCGR

Target: LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))

Alternative Name: LHCGR

Background: This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia.
Protein Interaction Partner: MPG, CHST9, GIPC1, SLC9A3R1, TSHR, LHCGR, LHB, GNAI2, GNAS, CGB, CGA, CANX, ARRB2,
Protein Size: 636

Molecular Weight: 69 kDa

Gene ID: 3973

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, cAMP Metabolic Process, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling