BID antibody (C-Term)
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- Target See all BID Antibodies
- BID (BH3 Interacting Domain Death Agonist (BID))
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Binding Specificity
- C-Term
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Reactivity
- Human, Dog, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BID antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Sequence
- LRNTSRSEED RNRDLATALE QLLQAYPRDM EKEKTMLVLA LLLAKKVASH
- Predicted Reactivity
- Dog: 86%, Horse: 86%, Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against BID. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product BID Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 241 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- BID (BH3 Interacting Domain Death Agonist (BID))
- Alternative Name
- BID (BID Products)
- Synonyms
- FP497 antibody, 2700049M22Rik antibody, AI875481 antibody, AU022477 antibody, BID antibody, bid antibody, si:ch211-238n5.6 antibody, fp497 antibody, xbid antibody, DKFZp469E066 antibody, BH3 interacting domain death agonist antibody, BH3 interacting domain death agonist S homeolog antibody, BID antibody, Bid antibody, bida antibody, bid.S antibody, bid antibody
- Background
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This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8), CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
Alias Symbols: FP497, MGC15319, MGC42355
Protein Interaction Partner: AHCYL1, REL, MCL1, BCL2, BCL2L1, GZMB, CASP3, BAG3, CAV1, SQSTM1, VCP, UBQLN2, RPA2, RPA1, UBC, TUBB2B, FBN3, RBM48, CRNKL1, ZHX1, C14orf1, SETDB1, PLEKHM1, TLE1, GBP2, GAPDH, CRMP1, ITCH, BID, BCL2L2, CASP8, CASP10, YWHAB, BCL2A1, CSNK1E, CASP2, BAK1, CS
Protein Size: 241 - Molecular Weight
- 27 kDa
- Gene ID
- 637
- NCBI Accession
- NM_197966, NP_932070
- UniProt
- B3KT21
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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