MEK1 antibody (N-Term)

Catalog No. ABIN2788667

The Rabbit Polyclonal anti-MEK1 antibody has been validated for WB. It is suitable to detect MEK1 in samples from Human, Mouse, Rat, Dog, Cow, Rabbit and Guinea Pig.

Quick Overview for MEK1 antibody (N-Term) (ABIN2788667)

Target: MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEK1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MEK1 Antibody

Binding Specificity: N-Term

Sequence: KKPTPIQLNP APDGSAVNGT SSAETNLEAL QKKLEELELD EQQRKRLEAF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Map2k1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Map2k1

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MEK1

Target: MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))

Alternative Name: Map2k1

Background: Map2k1 is a dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway.Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation.
Alias Symbols: MAPKK1, MEKK1, Mek1, Prkmk1
Protein Interaction Partner: Eed, Myod1, Map3k1, Cflar, Foxp3, Ksr1, Brap, Grin2b, Grin1, Nek10, Raf1, CPNE1, CPNE4,
Protein Size: 393

Molecular Weight: 43 kDa

Gene ID: 26395

NCBI Accession: NM_008927, NP_032953

UniProt: P31938

Pathways: MAPK Signaling, RTK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling