GPI antibody (C-Term)

Catalog No. ABIN2788668

This anti-GPI antibody is a Rabbit Polyclonal antibody detecting GPI in WB. Suitable for Human, Rat, Dog, Guinea Pig, Rabbit and Cow.

Quick Overview for GPI antibody (C-Term) (ABIN2788668)

Target: GPI (Glucose-6-Phosphate Isomerase (GPI))

Reactivity: Human, Rat, Dog, Guinea Pig, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPI antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GPI Antibody

Binding Specificity: C-Term

Sequence: SFDQWGVELG KQLAKKIEPE LDGSAQVTSH DASTNGLINF IKQQREARVQ

Predicted Reactivity: Cow: 92%, Dog: 86%, Guinea Pig: 100%, Human: 100%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against GPI. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GPI

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 558 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GPI

Target: GPI (Glucose-6-Phosphate Isomerase (GPI))

Alternative Name: GPI

Background: This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.
Alias Symbols: AMF, GNPI, NLK, PGI, PHI, SA36, SA-36
Protein Interaction Partner: HUWE1, ISG15, UBC, FUS, AMFR, MDM2, ASB15, BAG3, TMEM256, PDCD6IP, TPI1, ENO3, SUMO1, SUMO3, CCP110, CDK2, NEURL4, PCNA, AI837181, Csnk1e, GPI, IGFBP3, CSNK2A1, PARP14,
Protein Size: 558

Molecular Weight: 63 kDa

Gene ID: 2821

NCBI Accession: NM_000175, NP_000166

UniProt: P06744