HCCS antibody (C-Term)

Catalog No. ABIN2788670

The Rabbit Polyclonal anti-HCCS antibody is suitable to detect HCCS in samples from Human, Mouse, Rat, Dog, Horse, Pig, Rabbit, Cow and Guinea Pig. It has been validated for WB.

Quick Overview for HCCS antibody (C-Term) (ABIN2788670)

Target: HCCS (Holocytochrome C Synthase (HCCS))

Reactivity: Human, Mouse, Rat, Dog, Horse, Pig, Rabbit, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HCCS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HCCS Antibody

Binding Specificity: C-Term

Purpose: HCCS Antibody - C-terminal region

Sequence: PRARIRSWMG YELPFDRHDW IINRCGTEVR YVIDYYDGGE VNKDYQFTIL

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HCCS. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HCCS

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61090-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HCCS

Target: HCCS (Holocytochrome C Synthase (HCCS))

Alternative Name: HCCS

Background:

Background Information: The protein encoded by this gene is an enzyme that covalently links a heme group to the apoprotein of cytochrome c. Defects in this gene are a cause of microphthalmia syndromic type 7 (MCOPS7). Three transcript variants encoding the same protein have been found for this gene

Gene Name: Holocytochrome c synthase

Alternative Symbols: MLS, CCHL, MCOPS7, LSDMCA1

Protein Name: Cytochrome c-type heme lyase

Molecular Weight: 30kDa

Gene ID: 3052

NCBI Accession: NP_005324

UniProt: P53701