TPR antibody (C-Term)
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- Target See all TPR Antibodies
- TPR (Nucleoprotein TPR (TPR))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Cow, Dog, Rabbit, Rat, Guinea Pig, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TPR antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- SSEAGLEIDS QQEEEPVQAS DESDLPSTSQ DPPSSSSVDT SSSQPKPFRR
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against TPR. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human TPR
- Top Product
- Discover our top product TPR Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 2363 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TPR (Nucleoprotein TPR (TPR))
- Alternative Name
- TPR (TPR Products)
- Synonyms
- AtTPR antibody, TRANSLOCATED PROMOTER REGION antibody, YUP8H12R.12 antibody, YUP8H12R_12 antibody, nuclear pore anchor antibody, 2610029M07Rik antibody, C77892 antibody, translocated promoter region, nuclear basket protein antibody, nuclear pore anchor antibody, TPR antibody, NUA antibody, Tpr antibody
- Background
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This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias.
Alias Symbols: -
Protein Interaction Partner: STAU1, UBC, LGR4, MDM2, MAD1L1, EED, NPM1, LMNA, HDAC9, ITGA4, FN1, CBX7, BUD31, TAF15, TOP1, SNRPD1, SNRPA1, SRSF5, SFPQ, S100A9, RPL37A, RPL18A, RPL6, RBM4, RAN, PRKDC, NHP2L1, SEPT2, IK, HRAS, HNRNPU, HNRNPA2B1, EEF1D, EEF1B2, DDX3X, DDX1, DDB1, CIRBP,
Protein Size: 2363 - Molecular Weight
- 267 kDa
- Gene ID
- 7175
- NCBI Accession
- NM_003292, NP_003283
- UniProt
- P12270
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