SOD1 antibody (C-Term)

Catalog No. ABIN2788679

This anti-SOD1 antibody is a Rabbit Polyclonal antibody detecting SOD1 in WB. Suitable for Human, Mouse, Rat, Cow, Rabbit, Sheep, Dog, Horse, Guinea Pig, Goat and Zebrafish (Danio rerio).

Quick Overview for SOD1 antibody (C-Term) (ABIN2788679)

Target: SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Sheep, Dog, Horse, Guinea Pig, Goat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOD1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SOD1 Antibody

Binding Specificity: C-Term

Sequence: DVSIEDSVIS LSGDHCIIGR TLVVHEKADD LGKGGNEEST KTGNAGSRLA

Predicted Reactivity: Cow: 100%, Dog: 86%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against SOD1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SOD1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SOD1

Target: SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

Alternative Name: SOD1

Background: SOD1 binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in its gene have been implicated as causes of familial amyotrophic lateral sclerosis.
Alias Symbols: ALS, ALS1, IPOA, SOD, hSod1, homodimer
Protein Interaction Partner: SOD1, CRYAB, UBC, SMAD2, HDAC6, GSH1, OPTN, PRDX5, AHCYL1, TIAL1, PRDX2, SPTBN1, SOD2, PPP2CA, PPIA, PLS3, PRDX1, NME2, NME1, Hspa4l, Hspa4, Hspa2, Hspa1b, Hsph1, Dnaja1, Hspa8, Hspa5, Ccs, UBE3A, COMMD1, Stub1, SUMO4, DYNLT1, AMFR, MARCH5, RNF19A, PSMD4,
Protein Size: 154

Molecular Weight: 17 kDa

Gene ID: 6647

NCBI Accession: NM_000454, NP_000445

UniProt: P00441

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis