CDA antibody (C-Term)

Catalog No. ABIN2788688

This Rabbit Polyclonal antibody specifically detects CDA in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Guinea Pig, Horse, Saccharomyces cerevisiae and Zebrafish (Danio rerio).

Quick Overview for CDA antibody (C-Term) (ABIN2788688)

Target: CDA (Cytidine Deaminase (CDA))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CDA Antibody

Binding Specificity: C-Term

Purpose: CDA Antibody - C-terminal region

Sequence: SPCGACRQVM REFGTNWPVY MTKPDGTYIV MTVQELLPSS FGPEDLQKTQ

Predicted Reactivity: Cow: 86%, Guinea Pig: 92%, Horse: 83%, Human: 100%, Mouse: 86%, Rat: 92%, Yeast: 83%, Zebrafish: 90%

Characteristics: This is a rabbit polyclonal antibody against CDA. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CDA

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61133-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDA

Target: CDA (Cytidine Deaminase (CDA))

Alternative Name: CDA

Background:

Background Information: This gene encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias.

Gene Name: Cytidine deaminase

Alternative Symbols: CDD

Protein Name: Cytidine deaminase

Molecular Weight: 16kDa

Gene ID: 978

NCBI Accession: NP_001776

UniProt: P32320