ZAP70 antibody (Middle Region)
Quick Overview for ZAP70 antibody (Middle Region) (ABIN2788711)
Target
See all ZAP70 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Sequence
- TDKPRPMPMD TSVYESPYSD PEELKDKKLF LKRENLLVAD IELGCGNFGS
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Predicted Reactivity
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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Characteristics
- This is a rabbit polyclonal antibody against Zap70. It was validated on Western Blot.
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Purification
- Affinity Purified
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anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (C-Term) antibody
ZAP70 Reactivity: Human WB, ICC, ICFC Host: Mouse Monoclonal ZAP-03 unconjugated
anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (pTyr319) antibodyZAP70 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 169-390) antibodyZAP70 Reactivity: Human WB, FACS, ELISA Host: Mouse Monoclonal 1F3G9 unconjugated
anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 247-382) antibodyZAP70 Reactivity: Human IHC, FACS, ELISA, IF, StM, Coat Host: Mouse Monoclonal ZAP70-2035 unconjugated
anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 337-600) antibodyZAP70 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (pTyr493) antibodyZAP70 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 169-390) antibodyZAP70 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 6D9C2 unconjugated
anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 1-254) antibodyZAP70 Reactivity: Human IHC, FACS, IF, StM Host: Mouse Monoclonal 2F3-2 unconjugated
anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 1-300) antibodyZAP70 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (pTyr319) antibodyZAP70 Reactivity: Human WB, IHC, IF, IP Host: Rabbit Polyclonal unconjugated
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 618 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))
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Alternative Name
- Zap70
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Background
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Zap70 is a tyrosine kinase that plays an essential role in regulation of the adaptive immune response. Zap70 regulates motility, adhesion and cytokine expression of mature T cells, as well as thymocyte development. Zap70 contributes also to the development and activation of primary B lymphocytes.
Alias Symbols: 70 kDa, AI327364, Srk, TZK, ZAP-70, mrtle, mur
Protein Interaction Partner: Sla2, Was, Sla, Lck, Dlg1, Cbl, Slc4a1, Crkl, Cd247, Mapk14,
Protein Size: 618 -
Molecular Weight
- 70 kDa
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Gene ID
- 22637
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NCBI Accession
- NM_009539, NP_033565
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UniProt
- P43404
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Pathways
- TCR Signaling, Ubiquitin Proteasome Pathway
Target
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