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ZAP70 antibody (Middle Region)

The Rabbit Polyclonal anti-ZAP70 antibody (ABIN2788711) specifically detects ZAP70 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Rabbit, Horse, Guinea Pig and Dog samples.

Western Blotting (WB) image for anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (Middle Region) antibody (ABIN2788711) (ZAP70 antibody (Middle Region))

1 image

Catalog No. ABIN2788711

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Quick Overview for ZAP70 antibody (Middle Region) (ABIN2788711)

Target

See all ZAP70 Antibodies

ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

Reactivity

Human, Mouse, Rat, Cow, Rabbit, Horse, Guinea Pig, Dog

Host

Rabbit

Clonality

Polyclonal

Conjugate

This ZAP70 antibody is un-conjugated

Application

Western Blotting (WB)

Discover our top product ZAP70 Primary Antibody

Binding Specificity
42

35

29

27

21

19

16

10

10

9

8

8

7

6

5

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Middle Region

Sequence

TDKPRPMPMD TSVYESPYSD PEELKDKKLF LKRENLLVAD IELGCGNFGS

Predicted Reactivity

Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics

This is a rabbit polyclonal antibody against Zap70. It was validated on Western Blot.

Purification

Affinity Purified
anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (C-Term) antibody
ZAP70 Reactivity: Human WB, ICC, ICFC Host: Mouse Monoclonal ZAP-03 unconjugated

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (pTyr319) antibody
ZAP70 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 169-390) antibody
ZAP70 Reactivity: Human WB, FACS, ELISA Host: Mouse Monoclonal 1F3G9 unconjugated

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 247-382) antibody
ZAP70 Reactivity: Human IHC, FACS, ELISA, IF, StM, Coat Host: Mouse Monoclonal ZAP70-2035 unconjugated

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 337-600) antibody
ZAP70 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (pTyr493) antibody
ZAP70 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 169-390) antibody
ZAP70 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 6D9C2 unconjugated

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 1-254) antibody
ZAP70 Reactivity: Human IHC, FACS, IF, StM Host: Mouse Monoclonal 2F3-2 unconjugated

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 1-300) antibody
ZAP70 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated

anti-zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (AA 247-382) antibody
ZAP70 Reactivity: Human IHC Host: Rabbit Monoclonal 870R unconjugated Recombinant Antibody

Application Notes

Optimal working dilutions should be determined experimentally by the investigator.

Comment

Antigen size: 618 AA

Restrictions

For Research Use only
Format

Liquid

Concentration

Lot specific

Buffer

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice

Avoid repeated freeze-thaw cycles.

Storage

-20 °C

Storage Comment

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target

ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

Alternative Name

Zap70

Background

Zap70 is a tyrosine kinase that plays an essential role in regulation of the adaptive immune response. Zap70 regulates motility, adhesion and cytokine expression of mature T cells, as well as thymocyte development. Zap70 contributes also to the development and activation of primary B lymphocytes.
Alias Symbols: 70 kDa, AI327364, Srk, TZK, ZAP-70, mrtle, mur
Protein Interaction Partner: Sla2, Was, Sla, Lck, Dlg1, Cbl, Slc4a1, Crkl, Cd247, Mapk14,
Protein Size: 618

Molecular Weight

70 kDa

Gene ID

22637

NCBI Accession

NM_009539, NP_033565

UniProt

P43404

Pathways

TCR Signaling, Ubiquitin Proteasome Pathway