Chromosome 7 Open Reading Frame 20 (C7orf20) (N-Term) antibody

Catalog No. ABIN2788715

This Rabbit Polyclonal antibody specifically detects Chromosome 7 Open Reading Frame 20 in WB. It exhibits reactivity toward Human, Mouse, Rat, Guinea Pig, Cow, Horse, Zebrafish (Danio rerio) and Dog.

Quick Overview for Chromosome 7 Open Reading Frame 20 (C7orf20) (N-Term) antibody (ABIN2788715)

Target: Chromosome 7 Open Reading Frame 20 (C7orf20)

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Horse, Zebrafish (Danio rerio), Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: N-Term

Purpose: GET4 Antibody - N-terminal region

Sequence: ASVEKGDYYE AHQMYRTLFF RYMSQSKHTE ARELMYSGAL LFFSHGQQNS

Predicted Reactivity: Cow: 85%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rat: 93%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against GET4. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61198-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: Chromosome 7 Open Reading Frame 20 (C7orf20)

Alternative Name: GET4

Background:

Background Information: GET4 is a component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting.

Gene Name: Golgi to ER traffic protein 4 homolog (S. cerevisiae)

Alternative Symbols: CEE, TRC35, CGI-20, C7orf20

Protein Name: Golgi to ER traffic protein 4 homolog

Molecular Weight: 36kDa

Gene ID: 51608

NCBI Accession: NP_057033

UniProt: Q7L5D6