DHPS antibody (N-Term)

Catalog No. ABIN2788727

This Rabbit Polyclonal antibody specifically detects DHPS in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Horse, Pig, Cow and Rabbit.

Quick Overview for DHPS antibody (N-Term) (ABIN2788727)

Target: DHPS (Deoxyhypusine Synthase (DHPS))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Pig, Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DHPS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DHPS Antibody

Binding Specificity: N-Term

Purpose: DHPS Antibody - N-terminal region

Sequence: TTGFQATNFG RAVQQVNAMI EKKLEPLSQD EDQHADLTQS RRPLTSCTIF

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 79%, Pig: 100%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against DHPS. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DHPS

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61225-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DHPS

Target: DHPS (Deoxyhypusine Synthase (DHPS))

Alternative Name: DHPS

Background:

Background Information: This gene encodes a protein that is required for the formation of hypusine, a unique amino acid formed by the posttranslational modification of only one protein, eukaryotic translation initiation factor 5A. The encoded protein catalyzes the first step in hypusine formation by transferring the butylamine moiety of spermidine to a specific lysine residue of the eukaryotic translation initiation factor 5A precursor, forming an intermediate deoxyhypusine residue. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Name: Deoxyhypusine synthase

Alternative Symbols: DS, DHS, MIG13, NEDSSWI

Protein Name: Deoxyhypusine synthase

Molecular Weight: 35kDa

Gene ID: 1725

NCBI Accession: NP_037538

UniProt: P49366