Prohibitin antibody (C-Term)

Catalog No. ABIN2788746

The Rabbit Polyclonal anti-Prohibitin antibody has been validated for WB and IHC. It is suitable to detect Prohibitin in samples from Human, Mouse, Rat, Zebrafish (Danio rerio), Rabbit, Guinea Pig, Cow, Dog, Horse, Goat and Saccharomyces cerevisiae.

Quick Overview for Prohibitin antibody (C-Term) (ABIN2788746)

Target: Prohibitin (PHB)

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Rabbit, Guinea Pig, Cow, Dog, Horse, Goat, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prohibitin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Prohibitin Antibody

Binding Specificity: C-Term

Sequence: AKQVAQQEAE RARFVVEKAE QQKKAAIISA EGDSKAAELI ANSLATAGDG

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 85%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against Phb. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 272 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Prohibitin

Target: Prohibitin (PHB)

Alternative Name: Phb

Background: Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. Phb may play a role in regulating mitochondrial respiration activity and in aging.
Alias Symbols: BAP32, Bap32
Protein Interaction Partner: Eed, SNCA,
Protein Size: 272

Molecular Weight: 30 kDa

Gene ID: 18673

NCBI Accession: NM_008831, NP_032857

UniProt: P67778

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling