IL16 antibody (C-Term)

Catalog No. ABIN2788748

This anti-IL16 antibody is a Rabbit Polyclonal antibody detecting IL16 in WB. Suitable for Human, Pig, Goat and Horse.

Quick Overview for IL16 antibody (C-Term) (ABIN2788748)

Target: IL16 (Interleukin 16 (IL16))

Reactivity: Human, Pig, Goat, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL16 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IL16 Antibody

Binding Specificity: C-Term

Sequence: EILQLGGTAM QGLTRFEAWN IIKALPDGPV TIVIRRKSLQ SKETTAAGDS

Predicted Reactivity: Goat: 93%, Horse: 86%, Human: 100%, Pig: 85%

Characteristics: This is a rabbit polyclonal antibody against IL16. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human IL16

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 631 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IL16

Target: IL16 (Interleukin 16 (IL16))

Alternative Name: IL16

Background: The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants.
Alias Symbols: FLJ16806, FLJ42735, FLJ44234, LCF, NIL16, PRIL16, prIL-16
Protein Interaction Partner: UBC, KDM1A, SUV39H1, DMRTB1, GABPB1, CSNK2A1, CDK1, HDAC3, HSPA8, USHBP1, KCNA3, PPP1R12C, KCND2, SSSCA1, EFEMP2, PPP1R12B, IL16, GRIN2D, KCNJ10, KCNJ15, PPP1R12A, KCNJ2, CASP3, KCNJ4, KCND1, CD4, GRIN2C, GRIN2A, GRIN2B, CSNK2A2, KCNJ1,
Protein Size: 631

Molecular Weight: 67 kDa

Gene ID: 3603

NCBI Accession: NM_004513, NP_004504

UniProt: Q14005