Cathepsin L2 antibody (C-Term)

Catalog No. ABIN2788750

This Rabbit Polyclonal antibody specifically detects Cathepsin L2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Guinea Pig, Horse and Rabbit.

Quick Overview for Cathepsin L2 antibody (C-Term) (ABIN2788750)

Target: Cathepsin L2 (CTSL2)

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cathepsin L2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cathepsin L2 Antibody

Binding Specificity: C-Term

Purpose: CTSL2 Antibody - C-terminal region

Sequence: GFMARAFQYV KENGGLDSEE SYPYVAVDEI CKYRPENSVA NDTGFTVVAP

Predicted Reactivity: Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against CTSL2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61284-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Cathepsin L2

Target: Cathepsin L2 (CTSL2)

Alternative Name: CTSL2

Background:

Background Information: The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. This gene is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for this gene in tumor processes. Alternatively spliced variants, encoding the same protein, have been identified.

Gene Name: Cathepsin L2

Alternative Symbols: CTSU, CATL2, CTSL2

Protein Name: Cathepsin L2

Molecular Weight: 37kDa

Gene ID: 1515

NCBI Accession: NP_001324

UniProt: O60911

Pathways: Toll-Like Receptors Cascades