SRSF2 antibody (C-Term)

Catalog No. ABIN2788766

This Rabbit Polyclonal antibody specifically detects SRSF2 in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Dog, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for SRSF2 antibody (C-Term) (ABIN2788766)

Target: SRSF2 (serine/arginine-Rich Splicing Factor 2 (SRSF2))

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRSF2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SRSF2 Antibody

Binding Specificity: C-Term

Purpose: SFRS2 Antibody - C-terminal region

Sequence: KSKSSSVSRS RSRSRSRSRS RSPPPVSKRE SKSRSRSKSP PKSPEEEGAV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 91%

Characteristics: This is a rabbit polyclonal antibody against SFRS2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61320-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SRSF2

Target: SRSF2 (serine/arginine-Rich Splicing Factor 2 (SRSF2))

Alternative Name: SFRS2

Background:

Background Information: The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for this gene.

Gene Name: Serine/arginine-rich splicing factor 2

Alternative Symbols: SC35, PR264, SC-35, SFRS2, SFRS2A, SRp30b

Protein Name: Serine/arginine-rich splicing factor 2

Molecular Weight: 25kDa

Gene ID: 6427

NCBI Accession: NP_003007

UniProt: Q01130