TNFAIP3 antibody (C-Term)

Catalog No. ABIN2788768

This Rabbit Polyclonal antibody specifically detects TNFAIP3 in WB. It exhibits reactivity toward Human, Rat and Dog.

Quick Overview for TNFAIP3 antibody (C-Term) (ABIN2788768)

Target: TNFAIP3 (Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3))

Reactivity: Human, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFAIP3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TNFAIP3 Antibody

Binding Specificity: C-Term

Sequence: QENSEQGRRE GHAQNPMEPS VPQLSLMDVK CETPNCPFFM SVNTQPLCHE

Predicted Reactivity: Dog: 79%, Human: 100%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against TNFAIP3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human TNFAIP3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TNFAIP3

Target: TNFAIP3 (Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3))

Alternative Name: TNFAIP3

Background: This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene.
Alias Symbols: A20, AISBL, OTUD7C, TNFA1P2
Protein Size: 471

Molecular Weight: 51 kDa

Gene ID: 7128

NCBI Accession: NM_001270507, NP_001257436

UniProt: P21580

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Production of Molecular Mediator of Immune Response