EIF2B5 antibody (N-Term)

Catalog No. ABIN2788769

Cited in 1 publication. The Rabbit Polyclonal anti-EIF2B5 antibody (ABIN2788769) specifically detects EIF2B5 in WB. The antibody is reactive with Human, Rat, Cow, Horse and Dog samples.

Quick Overview for EIF2B5 antibody (N-Term) (ABIN2788769)

Target: EIF2B5 (Eukaryotic Translation Initiation Factor 2B, Subunit 5 Epsilon, 82kDa (EIF2B5))

Reactivity: Human, Rat, Cow, Horse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF2B5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EIF2B5 Antibody

Binding Specificity: N-Term

Sequence: GVVVSRANKR SGAGPGGSGG GGARGAEEEP PPPLQAVLVA DSFDRRFFPI

Predicted Reactivity: Cow: 85%, Dog: 92%, Horse: 85%, Human: 100%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against EIF2B5. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 721 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-EIF2B5 antibody (ABIN2788769)

Wortham, Stewart, Harris, Coldwell, Proud: "Stoichiometry of the eIF2B complex is maintained by mutual stabilization of subunits." in: The Biochemical journal, Vol. 473, Issue 5, pp. 571-80, (2016) (PubMed).

Target Details for EIF2B5

Target: EIF2B5 (Eukaryotic Translation Initiation Factor 2B, Subunit 5 Epsilon, 82kDa (EIF2B5))

Alternative Name: EIF2B5

Background: This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.
Alias Symbols: CACH, CLE, EIF-2B, EIF2Bepsilon, LVWM
Protein Interaction Partner: UBC, EGFR, EIF2B2, EIF2B3, EIF2B4, APP, CHMP2A, GSK3A, GSK3B, EIF2S2, CSNK1A1, CSNK2A2, CSNK2A1, EIF2B1,
Protein Size: 721

Molecular Weight: 79 kDa

Gene ID: 8893

NCBI Accession: NM_003907, NP_003898

UniProt: Q13144